3-Tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(diethylamino)propyl]amino}pyrido[2,3-d]pyrimidin-7-yl]urea

InChIKey	`ULIJLYCJYRQKBG-UHFFFAOYSA-N`
Compound Name	3-Tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(diethylamino)propyl]amino}pyrido[2,3-d]pyrimidin-7-yl]urea
Canonical SMILES	`CCN(CC)CCCNc1ncc2cc(-c3c(Cl)cccc3Cl)c(NC(=O)NC(C)(C)C)nc2n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	7
Pfam Stratification	Homologous
Avg pChEMBL	6.95
Source	BindingDB;ChEMBL;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P12931	SRC	Homo sapiens	Human	PF07714 PF00017 PF00018	7.1	IC50	ChEMBL;BindingDB
P11362	FGFR1	Homo sapiens	Human	PF07679 PF00047 PF07714	7.1	pIC50	TTD_MultiTarget
P21802	FGFR2	Homo sapiens	Human	PF07679 PF13927 PF07714	7.1	IC50	ChEMBL
P22455	FGFR4	Homo sapiens	Human	PF07679 PF13927 PF07714	7.1	IC50	ChEMBL
P22607	FGFR3	Homo sapiens	Human	PF21165 PF07679 PF13927 PF07714	7.1	IC50	ChEMBL
P09619	PDGFRB	Homo sapiens	Human	PF00047 PF13927 PF25305 PF07714	6.2	IC50	BindingDB
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	Clinical	TTD_MultiTarget	TTD_MultiTarget