InChIKey	ULGZDMOVFRHVEP-RWJQBGPGSA-N
Compound Name	Erythromycin
Canonical SMILES	CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	59
Pfam Stratification	Cross-Family
Avg pChEMBL	7.13
Source	BindingDB;ChEMBL

DrugBank ID	DB00199
Drug Name	Erythromycin
CAS Number	114-07-8
Groups	approved investigational vet_approved
ATC Codes	J01FA01 D10AF02 S01AA17 D10AF52
Description	Erythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists of [Azithromycin], [Clarithromycin], [Spiramycin] and others. It was originally discovered in 1952....

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Categories: Anti-Acne Preparations Anti-Acne Preparations for Topical Use Anti-Bacterial Agents Anti-Infective Agents Antibacterials for Systemic Use Antiinfectives for Systemic Use Antiinfectives for Treatment of Acne BSEP/ABCB11 Inhibitors BSEP/ABCB11 Substrates Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (moderate) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A5 Inhibitors Cytochrome P-450 CYP3A5 Inhibitors (moderate) Cytochrome P-450 CYP3A5 Substrates Cytochrome P-450 CYP3A7 Inhibitors Cytochrome P-450 CYP3A7 Inhibitors (moderate) Cytochrome P-450 CYP3A7 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Dermatologicals Enzyme Inhibitors Erythromycin and similars Erythromycins Gastrointestinal Agents Lactones Macrolide Antimicrobial Macrolides Macrolides, Lincosamides and Streptogramins Moderate Risk QTc-Prolonging Agents OATP1B1/SLCO1B1 Inhibitors OATP1B1/SLCO1B1 Substrates OATP1B3 inhibitors OATP1B3 substrates Ophthalmologicals P-glycoprotein inhibitors P-glycoprotein substrates Protein Synthesis Inhibitors QTc Prolonging Agents

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Cross-references: BindingDB: 86313 ChEBI: 42355 CHEMBL532 ChemSpider: 12041 Drugs Product Database (DPD): 8618 C01912 D00140 PDB: ERY PharmGKB: PA449493 PubChem:12560 PubChem:46508487 RxCUI: 4053 Therapeutic Targets Database: DAP000111 Wikipedia: Erythromycin ZINC: ZINC000085534336