InChIKey	ULFRLSNUDGIQQP-UHFFFAOYSA-N
Compound Name	Rizatriptan
Canonical SMILES	CN(C)CCc1c[nH]c2ccc(Cn3cncn3)cc12
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.46
Source	ChEMBL;BindingDB

DrugBank ID	DB00953
Drug Name	Rizatriptan
CAS Number	144034-80-0
Groups	approved investigational
ATC Codes	N02CC04
Description	Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT<sub>1B and 5-HT1D</sub> receptor agonist.[L46018] Used in the treatment of migraines, rizatriptan was first approved in the US in 1998.[L46018] Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), ...

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Categories: Agents that produce hypertension Amines Analgesics Antidepressive Agents Antimigraine Preparations Biogenic Amines Biogenic Monoamines Central Nervous System Depressants Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) Cytochrome P-450 Enzyme Inhibitors Drugs that are Mainly Renally Excreted Heterocyclic Compounds, Fused-Ring Indoles Migraine Disorders Monoamine Oxidase A Substrates Nervous System Neurotransmitter Agents Selective Serotonin 5-HT1 Receptor Agonists Selective Serotonin Agonists Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome Serotonin 1b Receptor Agonists Serotonin 1d Receptor Agonists Serotonin 5-HT1 Receptor Agonists Serotonin Agents Serotonin Modulators Serotonin Receptor Agonists Serotonin-1b and Serotonin-1d Receptor Agonist Triptans

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Cross-references: BindingDB: 50033437 ChEBI: 48273 CHEMBL905 ChemSpider: 4900 Drugs Product Database (DPD): 11899 Guide to Pharmacology: 51 IUPHAR: 51 D00675 PharmGKB: PA451264 PubChem:5078 PubChem:46506557 RxCUI: 88014 Therapeutic Targets Database: DAP000220 Wikipedia: Rizatriptan ZINC: ZINC000000005895