Molecule Details
| InChIKey | ULFIHHOZULSWER-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-cyclopropyl-1-{2-[(ethylcarbamoyl)amino]-6-fluoro-1H-1,3-benzodiazol-5-yl}-1H-imidazole-4-carboxamide |
| Canonical SMILES | CCNC(=O)Nc1nc2cc(-n3cnc(C(=O)NC4CC4)c3)c(F)cc2[nH]1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.7 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P0A0K8 | gyrB | Staphylococcus aureus | Pathogen | PF00204 PF00986 PF02518 PF01751 | 8.0 | Ki | ChEMBL |
| P20831 | gyrA | Staphylococcus aureus | Pathogen | PF03989 PF00521 | 8.0 | Ki | ChEMBL;BindingDB |
| P0AFI2 | parC | Escherichia coli (strain K12) | Pathogen | PF03989 PF00521 | 7.1 | Ki | BindingDB |