Molecule Details
| InChIKey | UJDRSYOCCUNRBX-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-(2-Chlorophenyl)-6-ethyl-4-(methoxymethyl)-3-methylpyrazolo[3,4-d]pyridazin-7-one |
| Canonical SMILES | CCn1nc(COC)c2c(C)n(-c3ccccc3Cl)nc2c1=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.5 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 7.5 | IC50 | ChEMBL |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 7.5 | IC50 | ChEMBL;BindingDB |
| Q08493 | PDE4C | Homo sapiens | Human | PF18100 PF00233 | 7.5 | IC50 | ChEMBL |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 7.5 | IC50 | ChEMBL |