Molecule Details
InChIKeyUIRCQOKSJDLYBB-UHFFFAOYSA-N
Compound Name10-methyl-9-phenyl-9H-acridine-2,7-diamine
Canonical SMILESCN1c2ccc(N)cc2C(c2ccccc2)c2cc(N)ccc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)50
Pfam Stratification Cross-Family
Avg pChEMBL6.46
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (50)
Target Gene Organism Category Pfam pChEMBL Type Source
O14757 CHEK1 Homo sapiens Human PF00069 9.0 Ki ChEMBL
P53667 LIMK1 Homo sapiens Human PF00412 PF00595 PF07714 7.6 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.6 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 7.2 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 7.1 Ki ChEMBL
P08581 MET Homo sapiens Human PF07714 PF01437 PF01403 PF01833 7.0 Ki ChEMBL
P16234 PDGFRA Homo sapiens Human PF07679 PF25305 PF07714 7.0 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 7.0 Ki ChEMBL
P29376 LTK Homo sapiens Human PF12810 PF07714 6.9 Ki ChEMBL
P51955 NEK2 Homo sapiens Human PF00069 6.9 Ki ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.6 Ki ChEMBL
Q5S007 LRRK2 Homo sapiens Human PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 6.6 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.5 Ki ChEMBL
Q9UHD2 TBK1 Homo sapiens Human PF00069 PF18394 PF18396 6.5 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.4 Ki ChEMBL
P09619 PDGFRB Homo sapiens Human PF00047 PF13927 PF25305 PF07714 6.4 Ki ChEMBL
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.4 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.4 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.4 Ki ChEMBL
P52333 JAK3 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.4 Ki ChEMBL
Q04759 PRKCQ Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.4 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.3 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
Q04771 ACVR1 Homo sapiens Human PF01064 PF07714 PF08515 6.3 Ki ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 6.3 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.3 Ki ChEMBL
Q8IU85 CAMK1D Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q9UQM7 CAMK2A Homo sapiens Human PF08332 PF00069 6.3 Ki ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.2 Ki ChEMBL
P04629 NTRK1 Homo sapiens Human PF13855 PF16920 PF07714 PF18613 6.2 Ki ChEMBL
Q06418 TYRO3 Homo sapiens Human PF00041 PF07679 PF07714 6.2 Ki ChEMBL
Q07912 TNK2 Homo sapiens Human PF09027 PF11555 PF07714 PF22931 PF14604 6.2 Ki ChEMBL
Q16539 MAPK14 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.2 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q02750 MAP2K1 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q05397 PTK2 Homo sapiens Human PF21477 PF00373 PF18038 PF03623 PF07714 6.1 Ki ChEMBL
Q06187 BTK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 6.1 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.1 Ki ChEMBL
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.0 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 6.0 Ki ChEMBL
P34947 GRK5 Homo sapiens Human PF00069 PF00615 6.0 Ki ChEMBL
P49336 CDK8 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.0 Ki ChEMBL
Q04912 MST1R Homo sapiens Human PF07714 PF01437 PF01403 PF01833 6.0 Ki ChEMBL
Q9UM73 ALK Homo sapiens Human PF12810 PF00629 PF07714 6.0 Ki ChEMBL