2-[4-[3-Methoxy-4-[[7-(3-methoxy-4-pyridinyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide

InChIKey	`UIFHDCIICKTEAL-UHFFFAOYSA-N`
Compound Name	2-[4-[3-Methoxy-4-[[7-(3-methoxy-4-pyridinyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide
Canonical SMILES	`COc1cc(C2CCN(CC(N)=O)CC2)ccc1Nc1ncc2ccc(-c3ccncc3OC)n2n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.88
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9UM73	ALK	Homo sapiens	Human	PF12810 PF00629 PF07714	7.4	IC50	ChEMBL;BindingDB
P06748	NPM1	Homo sapiens	Human	PF16276 PF03066	6.8	IC50	ChEMBL
P06213	INSR	Homo sapiens	Human	PF00757 PF17870 PF07714 PF01030	6.4	IC50	ChEMBL;BindingDB