N-(4-(3-Chloro-4-fluorophenylamino)quinazolin-6-yl)acrylamide

InChIKey	`UIAARIUTYORWEV-UHFFFAOYSA-N`
Compound Name	N-(4-(3-Chloro-4-fluorophenylamino)quinazolin-6-yl)acrylamide
Canonical SMILES	`C=CC(=O)Nc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.97
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P04626	ERBB2	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	9.1	pIC50	TTD_MultiTarget
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	8.8	IC50	ChEMBL;BindingDB