Molecule Details
InChIKeyUHCHLTQBLNUYRT-GFCCVEGCSA-N
Canonical SMILESCOc1cc2ncn(-c3cc(O[C@H](C)c4ccccc4Cl)c(C(N)=O)s3)c2cc1OC
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.66
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB07471
Drug Name5-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDE
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 28206 CHEMBL222419 ChemSpider: 10131669 PDB: BLZ PubChem:11957417 PubChem:99443942 ZINC: ZINC000016052682
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P53350 PLK1 Homo sapiens Human PF00069 PF00659 9.1 IC50 ChEMBL;BindingDB
Q9H4B4 PLK3 Homo sapiens Human PF00069 PF00659 8.2 IC50 ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P20248 CCNA2 Cyclin-A2 binder targets
P24941 CDK2 Cyclin-dependent kinase 2 binder targets