Molecule Details
InChIKeyUGHBIMSDMGHFIE-UHFFFAOYSA-N
Compound Name6-chloro-2-(2-fluoro-4-piperidin-3-ylphenyl)-1H-benzimidazole-4-carboxamide
Canonical SMILESNC(=O)c1cc(Cl)cc2[nH]c(-c3ccc(C4CCCNC4)cc3F)nc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL6.25
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
Q86V86 PIM3 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.6 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.4 Ki ChEMBL
P07333 CSF1R Homo sapiens Human PF00047 PF25305 PF07714 6.4 Ki ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.2 Ki ChEMBL
P06213 INSR Homo sapiens Human PF00757 PF17870 PF07714 PF01030 6.0 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.0 Ki ChEMBL
Q08881 ITK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 6.0 Ki ChEMBL
Q9UM73 ALK Homo sapiens Human PF12810 PF00629 PF07714 6.0 Ki ChEMBL