Molecule Details
| InChIKey | UFZTZBNSLXELAL-IOSLPCCCSA-N |
|---|---|
| Compound Name | beta,gamma-Methylene ATP |
| Canonical SMILES | Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO[P@](=O)(O)O[P@](=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.36 |
| Source | BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB03909 |
|---|---|
| Drug Name | Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate |
| CAS Number | nan |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Cross-references: BindingDB: 50370142 ChEBI: 40532 CHEMBL133463 ChemSpider: 82651 C13741 PDB: ACP PubChem:91532 PubChem:46506243 ZINC: ZINC000008295124
Target Activities (2)
DrugBank Target Actions (14)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| O00764 | PDXK | Pyridoxal kinase | binder | targets |
| O14983 | ATP2A1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | binder | targets |
| P00558 | PGK1 | Phosphoglycerate kinase 1 | binder | targets |
| P0A9J6 | P0A9J6 | Ribokinase | binder | targets |
| P15925 | P15925 | Folylpolyglutamate synthase | binder | targets |
| P33221 | P33221 | Formate-dependent phosphoribosylglycinamide formyltransferase | binder | targets |
| P45066 | P45066 | UDP-N-acetylmuramate--L-alanine ligase | binder | targets |
| P46859 | P46859 | Thermoresistant gluconokinase | binder | targets |
| P9WI81 | pknB | Serine/threonine-protein kinase PknB | binder | targets |
| Q12756 | Q12756 | Kinesin-like protein KIF1A | binder | targets |
| Q56310 | Q56310 | Chemotaxis protein CheA | binder | targets |
| Q8ZKR2 | Q8ZKR2 | Aminoimidazole riboside kinase | binder | targets |
| Q9X278 | Q9X278 | Probable butyrate kinase 2 | binder | targets |
| P06213 | INSR | Insulin receptor | inhibitor | targets |