Molecule Details
| InChIKey | UFSSPXFMMJZZDU-UHFFFAOYSA-N |
|---|---|
| Compound Name | US20250136581, Example 127 |
| Canonical SMILES | Cn1nnc(-c2ccc(C(F)F)cc2)c1COc1ccc(N2CCNC(=O)C2)nn1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.54 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P31644 | GABRA5 | Homo sapiens | Human | PF02931 PF02932 | 8.7 | Ki | BindingDB |
| P47869 | GABRA2 | Homo sapiens | Human | PF02931 PF02932 | 7.6 | Ki | BindingDB |
| P34903 | GABRA3 | Homo sapiens | Human | PF02931 PF02932 | 7.4 | Ki | BindingDB |
| P14867 | GABRA1 | Homo sapiens | Human | PF02931 PF02932 | 6.4 | Ki | BindingDB |