Molecule Details
| InChIKey | UFKSWYKDQZBJTH-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-[(3,5-Dibromo-4-hydroxyphenyl)methylidene]-5-iodo-1,2-dihydroindol-2-ol |
| Canonical SMILES | Oc1c(Br)cc(C=C2c3cc(I)ccc3NC2O)cc1Br |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.14 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P04049 | RAF1 | Homo sapiens | Human | PF00130 PF07714 PF02196 | 8.1 | IC50 | ChEMBL;BindingDB |
| Q9P1W9 | PIM2 | Homo sapiens | Human | PF00069 | 7.2 | IC50 | BindingDB |
| Q86V86 | PIM3 | Homo sapiens | Human | PF00069 | 7.0 | IC50 | BindingDB |
| P11309 | PIM1 | Homo sapiens | Human | PF00069 | 6.8 | IC50 | BindingDB |
| P15056 | BRAF | Homo sapiens | Human | PF00130 PF07714 PF02196 | 6.7 | IC50 | BindingDB |