N-hydroxy-4-(4-(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide

InChIKey	`UFKFLDDRYBWLPH-UHFFFAOYSA-N`
Compound Name	N-hydroxy-4-(4-(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide
Canonical SMILES	`O=C(NO)C1(S(=O)(=O)c2ccc(N3CCN(c4ccc(C(F)(F)F)cc4)CC3)cc2)CCOCC1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	7.68
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P45452	MMP13	Homo sapiens	Human	PF00045 PF00413 PF01471	9.2	IC50	ChEMBL;BindingDB
P08253	MMP2	Homo sapiens	Human	PF00040 PF00045 PF00413	7.9	pIC50	TTD_MultiTarget
P08254	MMP3	Homo sapiens	Human	PF00045 PF00413 PF01471	6.5	IC50	ChEMBL;BindingDB
P22894	MMP8	Homo sapiens	Human	PF00045 PF00413 PF01471	6.2	IC50	ChEMBL;BindingDB
P18843	nadE	Escherichia coli (strain K12)	Pathogen	PF02540	8.6	pIC50	TTD_MultiTarget