Molecule Details
InChIKeyUFGCTWUIESUHQP-UHFFFAOYSA-N
Compound Name5,15,17-Triazatetracyclo[8.7.0.02,7.011,16]heptadeca-1,3,5,7,9,11(16),12,14-octaene-9-carbonitrile
Canonical SMILESN#Cc1cc2cnccc2c2[nH]c3ncccc3c12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL6.5
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.9 IC50 ChEMBL;BindingDB
P49759 CLK1 Homo sapiens Human PF00069 6.8 IC50 ChEMBL;BindingDB
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.8 IC50 ChEMBL;BindingDB
P49760 CLK2 Homo sapiens Human PF00069 6.4 IC50 ChEMBL;BindingDB
Q13627 DYRK1A Homo sapiens Human PF00069 6.4 IC50 ChEMBL;BindingDB
Q00535 CDK5 Homo sapiens Human PF00069 6.1 IC50 ChEMBL
Q15078 CDK5R1 Homo sapiens Human PF03261 6.1 IC50 ChEMBL;BindingDB