Molecule Details
InChIKeyUEJXELMBDCXXAQ-UHFFFAOYSA-N
Compound Name3-(5-Cyclopropyl-1,2-oxazol-3-yl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
Canonical SMILESCC(C)n1nc(-c2cc(C3CC3)on2)c2c(N)ncnc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.19
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 8.4 IC50 ChEMBL;BindingDB
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 7.6 IC50 ChEMBL;BindingDB
P09769 FGR Homo sapiens Human PF07714 PF00017 PF00018 7.2 IC50 ChEMBL;BindingDB
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 7.1 IC50 ChEMBL;BindingDB
P36507 MAP2K2 Homo sapiens Human PF00069 7.1 IC50 ChEMBL;BindingDB
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 7.0 IC50 ChEMBL;BindingDB
P08631 HCK Homo sapiens Human PF07714 PF00017 PF00018 6.9 IC50 ChEMBL;BindingDB
Q02750 MAP2K1 Homo sapiens Human PF00069 6.8 IC50 ChEMBL;BindingDB
Q15418 RPS6KA1 Homo sapiens Human PF00069 PF00433 6.5 IC50 ChEMBL;BindingDB