3-Cyclopentylidene-1,2-dihydrocyclopenta[b]quinoline-9-carboxylic acid

InChIKey	`UEIRKXUBXCSHJE-UHFFFAOYSA-N`
Compound Name	3-Cyclopentylidene-1,2-dihydrocyclopenta[b]quinoline-9-carboxylic acid
Canonical SMILES	`O=C(O)c1c2c(nc3ccccc13)C(=C1CCCC1)CC2`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	19
Pfam Stratification	Cross-Family
Avg pChEMBL	6.36
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q06418	TYRO3	Homo sapiens	Human	PF00041 PF07679 PF07714	7.2	Ki	ChEMBL
Q9H4B4	PLK3	Homo sapiens	Human	PF00069 PF00659	7.1	Ki	ChEMBL
P53350	PLK1	Homo sapiens	Human	PF00069 PF00659	6.6	Ki	ChEMBL
O00311	CDC7	Homo sapiens	Human	PF00069	6.5	Ki	ChEMBL
O43781	DYRK3	Homo sapiens	Human	PF00069	6.5	Ki	ChEMBL
Q96SB4	SRPK1	Homo sapiens	Human	PF00069	6.5	Ki	ChEMBL
P43405	SYK	Homo sapiens	Human	PF07714 PF00017	6.4	Ki	ChEMBL
Q13131	PRKAA1	Homo sapiens	Human	PF16579 PF21147 PF00069	6.4	Ki	ChEMBL
Q16644	MAPKAPK3	Homo sapiens	Human	PF00069	6.4	Ki	ChEMBL
P68400	CSNK2A1	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
Q96GD4	AURKB	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
Q06187	BTK	Homo sapiens	Human	PF00779 PF00169 PF07714 PF00017 PF00018	6.2	Ki	ChEMBL
Q9BZL6	PRKD2	Homo sapiens	Human	PF00130 PF00169 PF00069 PF25525	6.2	Ki	ChEMBL
P49841	GSK3B	Homo sapiens	Human	PF00069	6.1	Ki	ChEMBL
Q13557	CAMK2D	Homo sapiens	Human	PF08332 PF00069	6.1	Ki	ChEMBL
P30530	AXL	Homo sapiens	Human	PF00041 PF13927 PF07714	6.0	Ki	ChEMBL
P31749	AKT1	Homo sapiens	Human	PF00169 PF00069 PF00433	6.0	Ki	ChEMBL
P31751	AKT2	Homo sapiens	Human	PF00169 PF00069 PF00433	6.0	Ki	ChEMBL
Q9Y6M4	CSNK1G3	Homo sapiens	Human	PF12605 PF00069	6.0	Ki	ChEMBL