Molecule Details
| InChIKey | UDGLYSKKNULXQB-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-[[4-(Ethylaminocarbamoyl)phenyl]methyl]-3-quinolin-8-ylurea |
| Canonical SMILES | CCNNC(=O)c1ccc(CNC(=O)Nc2cccc3cccnc23)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.31 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O15379 | HDAC3 | Homo sapiens | Human | PF00850 | 9.1 | IC50 | ChEMBL;BindingDB |
| Q13547 | HDAC1 | Homo sapiens | Human | PF00850 | 8.5 | IC50 | ChEMBL;BindingDB |
| Q92769 | HDAC2 | Homo sapiens | Human | PF00850 | 8.2 | IC50 | ChEMBL;BindingDB |
| Q9UBN7 | HDAC6 | Homo sapiens | Human | PF00850 PF02148 | 7.5 | IC50 | ChEMBL;BindingDB |