Molecule Details
InChIKeyUCHQCSDTPQKAKL-UHFFFAOYSA-N
Compound Name3-((5-(6-((3-Chlorophenyl)amino)pyrazinyl)-3-pyridinyl)amino)-1-propanol
Canonical SMILESOCCCNc1cncc(-c2cncc(Nc3cccc(Cl)c3)n2)c1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.98
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 8.3 IC50 ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 8.3 IC50 ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 7.1 IC50 ChEMBL
P21802 FGFR2 Homo sapiens Human PF07679 PF13927 PF07714 6.7 IC50 ChEMBL;BindingDB
P09619 PDGFRB Homo sapiens Human PF00047 PF13927 PF25305 PF07714 6.4 IC50 ChEMBL;BindingDB
P16234 PDGFRA Homo sapiens Human PF07679 PF25305 PF07714 6.4 IC50 ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.3 IC50 ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.3 IC50 ChEMBL
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 Clinical TTD_MultiTarget TTD_MultiTarget