Molecule Details
InChIKeyUCEGDYDPOSBUTP-UHFFFAOYSA-N
Compound Name3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione
Canonical SMILESCn1nc(-c2ccc(Cl)cc2)nc2c(=O)n(C)c(=O)nc1-2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL6.66
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P84022 SMAD3 Homo sapiens Human PF03165 PF03166 7.4 IC50 ChEMBL;BindingDB
P35222 CTNNB1 Homo sapiens Human PF00514 6.5 IC50 ChEMBL;BindingDB
Q9NQB0 TCF7L2 Homo sapiens Human PF08347 PF00505 6.5 IC50 ChEMBL
O95977 S1PR4 Homo sapiens Human PF00001 6.4 IC50 ChEMBL
O95136 S1PR2 Homo sapiens Human PF00001 6.1 IC50 ChEMBL;BindingDB
P9WHH9 lpdC Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) Pathogen PF07992 PF02852 7.0 IC50 ChEMBL;BindingDB