Molecule Details
InChIKeyUBCHPRBFMUDMNC-UHFFFAOYSA-N
Compound NameRimantadine
Canonical SMILESCC(N)C12CC3CC(CC(C3)C1)C2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL7.28
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB00478
Drug NameRimantadine
CAS Number13392-28-4
Groups approved
ATC Codes J05AC02
DescriptionAn RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.

Categories: Adamantanes Anti-Infective Agents Antiinfectives for Systemic Use Antiviral Agents Bridged-Ring Compounds Cyclic Amines Cycloparaffins Enzyme Inhibitors Influenza A M2 Protein Inhibitor M2 Protein Inhibitors Nucleic Acid Synthesis Inhibitors
Cross-references: BindingDB: 50216627 ChEBI: 94440 CHEMBL959 ChemSpider: 4893 C07236 D08483 PharmGKB: PA164748038 PubChem:5071 PubChem:46505973 RxCUI: 9386 Therapeutic Targets Database: DAP001087 Wikipedia: Rimantadine
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P03437 HA Influenza A virus (strain A/Aichi/2/1968 H3N2) Pathogen PF00509 7.5 IC50 BindingDB
P06821 M Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) Pathogen PF00599 7.0 Kd ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P21430 P21430 Matrix protein 2 other/unknown targets