Molecule Details
InChIKeyUAOIPNOTWOYAMU-LBPRGKRZSA-N
Compound NamePha-533533
Canonical SMILESC[C@H](C(=O)Nc1cc(C2CC2)[nH]n1)c1ccc(N2CCCC2=O)cc1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)11
Pfam Stratification Cross-Family
Avg pChEMBL7.15
SourceChEMBL;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
P06493 CDK1 Homo sapiens Human PF00069 7.4 pIC50 TTD_MultiTarget
P20248 CCNA2 Homo sapiens Human PF02984 PF00134 PF16500 7.4 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 7.4 pIC50 TTD_MultiTarget
P78396 CCNA1 Homo sapiens Human PF02984 PF00134 PF16500 7.4 IC50 ChEMBL
O96020 CCNE2 Homo sapiens Human PF02984 PF00134 7.3 IC50 ChEMBL
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 7.3 IC50 ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 7.2 IC50 ChEMBL
Q15078 CDK5R1 Homo sapiens Human PF03261 7.2 IC50 ChEMBL
O95067 CCNB2 Homo sapiens Human PF02984 PF00134 6.7 IC50 ChEMBL
P14635 CCNB1 Homo sapiens Human PF02984 PF00134 6.7 IC50 ChEMBL
Q8WWL7 CCNB3 Homo sapiens Human PF02984 PF00134 6.7 IC50 ChEMBL