Molecule Details
| InChIKey | UAFJMITWUKBNEN-NOLJZWGESA-N |
|---|---|
| Compound Name | 3-[(1S,2R)-2-(2-methoxyethyl)cyclopropyl]-5-[[(2S)-pyrrolidin-2-yl]methoxy]pyridine |
| Canonical SMILES | COCC[C@H]1C[C@@H]1c1cncc(OC[C@@H]2CCCN2)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.75 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P43681 | CHRNA4 | Homo sapiens | Human | PF02931 PF02932 | 7.0 | IC50 | ChEMBL;BindingDB |
| P17787 | CHRNB2 | Homo sapiens | Human | PF02931 PF02932 | 6.8 | IC50 | ChEMBL |
| P32297 | CHRNA3 | Homo sapiens | Human | PF02931 PF02932 | 6.7 | IC50 | ChEMBL |
| Q05901 | CHRNB3 | Homo sapiens | Human | PF02931 PF02932 | 6.7 | IC50 | ChEMBL |
| Q15825 | CHRNA6 | Homo sapiens | Human | PF02931 PF02932 | 6.7 | IC50 | ChEMBL |