Molecule Details
InChIKeyUAFDMWGGQQODTL-UHFFFAOYSA-N
Compound Name7-Methylsulfonyl-16-(piperidin-4-ylmethyl)-20-propan-2-yl-10-oxa-2,16,18,22,23,24-hexazatetracyclo[15.6.1.04,9.019,23]tetracosa-1(24),4(9),5,7,17,19,21-heptaene
Canonical SMILESCC(C)c1cnn2c3nc(nc12)N(CC1CCNCC1)CCCCCOc1cc(S(C)(=O)=O)ccc1CN3
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL8.22
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
Q00535 CDK5 Homo sapiens Human PF00069 8.6 Ki ChEMBL
Q15078 CDK5R1 Homo sapiens Human PF03261 8.6 Ki ChEMBL
O60563 CCNT1 Homo sapiens Human PF00134 PF21797 8.6 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 8.6 Ki ChEMBL
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 8.3 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 8.3 Ki ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 7.7 Ki ChEMBL
P51946 CCNH Homo sapiens Human PF16899 PF00134 7.7 Ki ChEMBL
P51948 MNAT1 Homo sapiens Human PF25811 PF06391 PF17121 7.7 Ki ChEMBL