Molecule Details
| InChIKey | TZZSQUATPYDROZ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-Hydroxy-1,2,3,4-tetrahydroquinazoline-2,4-dione |
| Canonical SMILES | O=c1[nH]c2ccccc2c(=O)n1O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.43 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P28715 | ERCC5 | Homo sapiens | Human | PF00867 PF00752 | 9.8 | IC50 | ChEMBL;BindingDB |
| O43570 | CA12 | Homo sapiens | Human | PF00194 | 7.0 | Ki | ChEMBL;BindingDB |
| P39748 | FEN1 | Homo sapiens | Human | PF00867 PF00752 | 6.6 | IC50 | ChEMBL;BindingDB |
| Q16790 | CA9 | Homo sapiens | Human | PF00194 | 6.3 | Ki | ChEMBL;BindingDB |