Molecule Details
InChIKeyTZYWCYJVHRLUCT-VABKMULXSA-N
Compound NameMG-132
Canonical SMILESCC(C)C[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)23
Pfam Stratification Cross-Family
Avg pChEMBL7.32
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (23)
Target Gene Organism Category Pfam pChEMBL Type Source
P07711 CTSL Homo sapiens Human PF08246 PF00112 9.8 IC50 ChEMBL;BindingDB
P43235 CTSK Homo sapiens Human PF08246 PF00112 8.8 Ki ChEMBL
P28074 PSMB5 Homo sapiens Human PF00227 8.1 IC50 ChEMBL;BindingDB
P49721 PSMB2 Homo sapiens Human PF00227 7.3 Ki ChEMBL;BindingDB
A5LHX3 PSMB11 Homo sapiens Human PF00227 7.2 IC50 ChEMBL
O14818 PSMA7 Homo sapiens Human PF00227 PF10584 7.2 IC50 ChEMBL
P25786 PSMA1 Homo sapiens Human PF00227 PF10584 7.2 IC50 ChEMBL
P25787 PSMA2 Homo sapiens Human PF00227 PF10584 7.2 IC50 ChEMBL
P25788 PSMA3 Homo sapiens Human PF00227 PF10584 7.2 IC50 ChEMBL
P25789 PSMA4 Homo sapiens Human PF00227 PF10584 7.2 IC50 ChEMBL
P28062 PSMB8 Homo sapiens Human PF00227 7.2 IC50 ChEMBL
P28065 PSMB9 Homo sapiens Human PF00227 7.2 IC50 ChEMBL
P28066 PSMA5 Homo sapiens Human PF00227 PF10584 7.2 IC50 ChEMBL
P28070 PSMB4 Homo sapiens Human PF00227 7.2 IC50 ChEMBL
P28072 PSMB6 Homo sapiens Human PF00227 7.2 IC50 ChEMBL
P40306 PSMB10 Homo sapiens Human PF12465 PF00227 7.2 IC50 ChEMBL
P49720 PSMB3 Homo sapiens Human PF00227 7.2 IC50 ChEMBL
P60900 PSMA6 Homo sapiens Human PF00227 PF10584 7.2 IC50 ChEMBL
Q8TAA3 PSMA8 Homo sapiens Human PF00227 PF10584 7.2 IC50 ChEMBL
Q99436 PSMB7 Homo sapiens Human PF12465 PF00227 7.2 IC50 ChEMBL
P20618 PSMB1 Homo sapiens Human PF00227 6.9 IC50 ChEMBL;BindingDB
P07858 CTSB Homo sapiens Human PF00112 PF08127 6.6 Ki ChEMBL;BindingDB
P17655 CAPN2 Homo sapiens Human PF01067 PF13833 PF00648 6.2 Ki ChEMBL;BindingDB