Molecule Details
| InChIKey | TXWSATBBJRPVTL-UVHMKAGCSA-N |
|---|---|
| Compound Name | 2-[4-[(E)-[[4-[2-(4-chloroanilino)thiazol-4-yl]benzoyl]hydrazono]methyl]phenoxy]acetic acid |
| Canonical SMILES | O=C(O)COc1ccc(/C=N/NC(=O)c2ccc(-c3csc(Nc4ccc(Cl)cc4)n3)cc2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.43 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P35236 | PTPN7 | Homo sapiens | Human | PF00102 | 6.7 | IC50 | ChEMBL;BindingDB |
| Q05209 | PTPN12 | Homo sapiens | Human | PF00102 | 6.5 | IC50 | ChEMBL |
| Q9Y6K1 | DNMT3A | Homo sapiens | Human | PF17980 PF00145 PF22855 PF21255 PF00855 | 6.5 | IC50 | BindingDB |
| Q9Y2R2 | PTPN22 | Homo sapiens | Human | PF00102 | 6.4 | IC50 | ChEMBL;BindingDB |
| Q07820 | MCL1 | Homo sapiens | Human | PF00452 | 6.0 | IC50 | ChEMBL |