TXRZDWUIAYQQJI-UHFFFAOYSA-N

InChIKey	`TXRZDWUIAYQQJI-UHFFFAOYSA-N`
Canonical SMILES	`CC(=O)Nc1cc(Nc2nc(-c3ccccn3)nc3[nH]ccc23)ccn1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Cross-Family
Avg pChEMBL	8.18
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P36897	TGFBR1	Homo sapiens	Human	PF01064 PF00069 PF08515	9.1	IC50	ChEMBL;BindingDB
P37173	TGFBR2	Homo sapiens	Human	PF08917 PF07714	7.3	IC50	ChEMBL;BindingDB