Molecule Details
InChIKeyTXCYUSKWBHUVEP-CYBMUJFWSA-N
Compound NameFacinicline
Canonical SMILESO=C(N[C@@H]1CN2CCC1CC2)c1n[nH]c2ccccc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.39
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB05586
Drug NameFacinicline
CAS Number677306-35-3
Groups investigational
ATC Codes nan
Descriptionnan
Categories: Bridged-Ring Compounds Heterocyclic Compounds, Fused-Ring Pyrazoles
Cross-references: BindingDB: 50393245 CHEMBL2151439 ChemSpider: 8145949 ZINC: ZINC000034057058
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P46098 HTR3A Homo sapiens Human PF02931 PF02932 8.6 IC50 ChEMBL;BindingDB
P36544 CHRNA7 Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P36544 CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 antagonist targets