Molecule Details
InChIKeyTWVQBTCNHBHZAV-JRBJCYRMSA-N
Canonical SMILESC[C@@H](Nc1ncnc2cc(=O)n(C34CC(C3)C4)cc12)c1cccc(C(F)F)c1F
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL8.15
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P01116 KRAS Homo sapiens Human PF00071 8.2 IC50 ChEMBL
Q07889 SOS1 Homo sapiens Human PF00617 PF00618 PF00621 PF22697 8.2 IC50 ChEMBL;BindingDB