Molecule Details
InChIKeyTWKWEBMGDALHPN-UHFFFAOYSA-N
Compound NameSrpkin-1
Canonical SMILESCCc1cc2c(cc1-c1cccc(S(=O)(=O)F)c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.02
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9UPE1 SRPK3 Homo sapiens Human PF00069 8.3 IC50 ChEMBL
Q9UM73 ALK Homo sapiens Human PF12810 PF00629 PF07714 8.0 IC50 ChEMBL;BindingDB
Q96SB4 SRPK1 Homo sapiens Human PF00069 7.5 IC50 ChEMBL;BindingDB
P78362 SRPK2 Homo sapiens Human PF00069 7.0 IC50 ChEMBL;BindingDB
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.8 IC50 ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.7 IC50 ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.5 IC50 ChEMBL
P49759 CLK1 Homo sapiens Human PF00069 6.4 IC50 ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.0 IC50 ChEMBL