Molecule Details
InChIKeyTWCARTFPHQNBPF-UHFFFAOYSA-N
Compound NameN-[2-[(5-isoquinolin-6-yl-3-pyridinyl)oxy]ethyl]methanesulfonamide
Canonical SMILESCS(=O)(=O)NCCOc1cncc(-c2ccc3cnccc3c2)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)16
Pfam Stratification Homologous
Avg pChEMBL6.62
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (16)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 8.3 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 7.3 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 7.3 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.8 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.7 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.6 Ki ChEMBL
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 6.6 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.3 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.2 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.1 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.1 Ki ChEMBL