Molecule Details
| InChIKey | TVZCRIROJQEVOT-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-Hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydro-2H-1-benzopyran-6-carbonitrile |
| Canonical SMILES | CC1(C)Oc2ccc(C#N)cc2C(N2CCCC2=O)C1O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.97 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O60706 | ABCC9 | Homo sapiens | Human | PF00664 PF00005 | 7.0 | IC50 | ChEMBL |
| Q09428 | ABCC8 | Homo sapiens | Human | PF00664 PF00005 | 7.0 | IC50 | ChEMBL |
| Q14654 | KCNJ11 | Homo sapiens | Human | PF01007 PF17655 | 7.0 | IC50 | ChEMBL |
| Q15842 | KCNJ8 | Homo sapiens | Human | PF01007 PF17655 | 7.0 | IC50 | ChEMBL |