Molecule Details
| InChIKey | TVQVEBXIMQEOQV-HNNXBMFYSA-N |
|---|---|
| Compound Name | 3-[[(2S)-azetidin-2-yl]methoxy]-5-hex-1-ynyl-2-methylpyridine |
| Canonical SMILES | CCCCC#Cc1cnc(C)c(OC[C@@H]2CCN2)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.17 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q15822 | CHRNA2 | Homo sapiens | Human | PF02931 PF02932 | 7.8 | Ki | ChEMBL |
| P17787 | CHRNB2 | Homo sapiens | Human | PF02931 PF02932 | 7.2 | IC50 | ChEMBL |
| P43681 | CHRNA4 | Homo sapiens | Human | PF02931 PF02932 | 7.2 | IC50 | ChEMBL;BindingDB |
| P32297 | CHRNA3 | Homo sapiens | Human | PF02931 PF02932 | 6.4 | Ki | ChEMBL |