Molecule Details
| InChIKey | TVMSHOVHQZAERD-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-[4-amino-5-(4-bromophenyl)-2-sulfanylidene-3H-pyrrolo[2,3-d]pyrimidin-7-yl]benzenesulfonamide |
| Canonical SMILES | Nc1nc(=S)[nH]c2c1c(-c1ccc(Br)cc1)cn2-c1ccc(S(N)(=O)=O)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.88 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q16790 | CA9 | Homo sapiens | Human | PF00194 | 7.4 | Ki | ChEMBL;BindingDB |
| P00918 | CA2 | Homo sapiens | Human | PF00194 | 7.0 | Ki | ChEMBL;BindingDB |
| P00915 | CA1 | Homo sapiens | Human | PF00194 | 6.6 | Ki | ChEMBL;BindingDB |
| O43570 | CA12 | Homo sapiens | Human | PF00194 | 6.5 | Ki | ChEMBL;BindingDB |