Molecule Details
InChIKeyTUFOXZXSKHTTLC-NSHDSACASA-N
Compound Name(S)-2-({4-[3-(2,4-Diamino-furo[2,3-d]pyrimidin-5-yl)-propyl]-thiophene-2-carbonyl}-amino)-pentanedioic acid
Canonical SMILESNc1nc(N)c2c(CCCc3csc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c3)coc2n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)4
Pfam Stratification Cross-Family
Avg pChEMBL7.23
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (4)
Target Gene Organism Category Pfam pChEMBL Type Source
P14207 FOLR2 Homo sapiens Human PF03024 7.8 IC50 ChEMBL;BindingDB
P41440 SLC19A1 Homo sapiens Human PF01770 7.3 IC50 ChEMBL;BindingDB
P22102 GART Homo sapiens Human PF00586 PF02769 PF00551 PF01071 PF02843 PF02844 7.1 IC50 ChEMBL;BindingDB
P15328 FOLR1 Homo sapiens Human PF03024 6.8 IC50 ChEMBL;BindingDB