4-[4-(3-Quinolin-4-ylpyrazolo[1,5-a]pyrimidin-6-yl)phenyl]morpholine

InChIKey	`SZVLDZCYMADNPG-UHFFFAOYSA-N`
Compound Name	4-[4-(3-Quinolin-4-ylpyrazolo[1,5-a]pyrimidin-6-yl)phenyl]morpholine
Canonical SMILES	`c1ccc2c(-c3cnn4cc(-c5ccc(N6CCOCC6)cc5)cnc34)ccnc2c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.94
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P37173	TGFBR2	Homo sapiens	Human	PF08917 PF07714	7.6	IC50	ChEMBL;BindingDB
P36897	TGFBR1	Homo sapiens	Human	PF01064 PF00069 PF08515	6.8	IC50	ChEMBL;BindingDB
P36896	ACVR1B	Homo sapiens	Human	PF01064 PF00069 PF08515	6.5	IC50	ChEMBL;BindingDB