Molecule Details
InChIKeySZFYZDIPRMLBDC-UHFFFAOYSA-N
Compound Name6-(6-chloroimidazo[1,2-a]pyridin-3-yl)-N-piperidin-3-ylpyridin-2-amine
Canonical SMILESClc1ccc2ncc(-c3cccc(NC4CCCNC4)n3)n2c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.29
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P36888 FLT3 Homo sapiens Human PF00047 PF07714 8.9 Kd ChEMBL;BindingDB
Q9NWZ3 IRAK4 Homo sapiens Human PF07714 8.1 IC50 ChEMBL;BindingDB
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 8.0 IC50 ChEMBL;BindingDB
P51451 BLK Homo sapiens Human PF07714 PF00017 PF00018 7.4 IC50 ChEMBL;BindingDB
P09619 PDGFRB Homo sapiens Human PF00047 PF13927 PF25305 PF07714 7.2 IC50 ChEMBL;BindingDB
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 6.8 Kd ChEMBL;BindingDB
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 6.8 IC50 ChEMBL;BindingDB
P50613 CDK7 Homo sapiens Human PF00069 6.2 IC50 ChEMBL
P51946 CCNH Homo sapiens Human PF16899 PF00134 6.2 IC50 ChEMBL;BindingDB