Molecule Details
InChIKeySYLTYCLPHHSEIJ-UHFFFAOYSA-N
Compound NameN-(5-methyl-2-pyridinyl)-6-nitro-1H-benzimidazol-2-amine
Canonical SMILESCc1ccc(Nc2nc3ccc([N+](=O)[O-])cc3[nH]2)nc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)27
Pfam Stratification Cross-Family
Avg pChEMBL6.5
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (27)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 8.0 Ki ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 7.3 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 7.2 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 6.9 Ki ChEMBL
Q9HCP0 CSNK1G1 Homo sapiens Human PF12605 PF00069 6.8 Ki ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.8 Ki ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 6.7 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.6 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q9NWZ3 IRAK4 Homo sapiens Human PF07714 6.6 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q08881 ITK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 6.4 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.3 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.1 Ki ChEMBL
P07333 CSF1R Homo sapiens Human PF00047 PF25305 PF07714 6.1 Ki ChEMBL
P09619 PDGFRB Homo sapiens Human PF00047 PF13927 PF25305 PF07714 6.1 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.1 Ki ChEMBL
P51957 NEK4 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q5S007 LRRK2 Homo sapiens Human PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 6.1 Ki ChEMBL
Q9HBY8 SGK2 Homo sapiens Human PF00069 PF00433 6.1 Ki ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.0 Ki ChEMBL
Q96SB4 SRPK1 Homo sapiens Human PF00069 6.0 Ki ChEMBL