Molecule Details
| InChIKey | SWVWXQFAJXFRCG-CABCVRRESA-N |
|---|---|
| Compound Name | US20230339978, Example 1 |
| Canonical SMILES | O=C(Nc1cc2cc(-c3cnc4[nH]ccc4c3)ccn2n1)[C@@H]1C[C@@H]1F |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.17 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00519 | ABL1 | Homo sapiens | Human | PF08919 PF07714 PF00017 PF00018 | 9.2 | IC50 | BindingDB |
| O43353 | RIPK2 | Homo sapiens | Human | PF00619 PF07714 | 8.0 | IC50 | BindingDB |
| Q5S007 | LRRK2 | Homo sapiens | Human | PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 | 7.4 | IC50 | BindingDB |