Molecule Details
InChIKeySVWVGWHDUPYUFQ-UHFFFAOYSA-N
Compound Name15-Methyl-4-(methylsulfonylmethyl)-8-(naphthalene-1-carbonyl)-8,12,17-triazatetracyclo[8.6.1.02,7.014,17]heptadeca-1(16),2(7),3,5,10,14-hexaen-13-one
Canonical SMILESCc1cc2n3c(c[nH]c(=O)c13)CN(C(=O)c1cccc3ccccc13)c1ccc(CS(C)(=O)=O)cc1-2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)4
Pfam Stratification Homologous
Avg pChEMBL6.95
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (4)
Target Gene Organism Category Pfam pChEMBL Type Source
Q58F21 BRDT Homo sapiens Human PF17035 PF17105 PF00439 7.2 IC50 ChEMBL
O60885 BRD4 Homo sapiens Human PF17035 PF17105 PF00439 7.0 IC50 ChEMBL
Q15059 BRD3 Homo sapiens Human PF17035 PF00439 6.9 IC50 ChEMBL
P25440 BRD2 Homo sapiens Human PF17035 PF00439 6.6 IC50 ChEMBL