Molecule Details
InChIKeySVUIYNKSDCANAY-UHFFFAOYSA-N
Compound Name4-[2-[(2-Chlorophenoxy)methyl]-4-methyl-1,3-thiazol-5-yl]pyrimidin-2-amine
Canonical SMILESCc1nc(COc2ccccc2Cl)sc1-c1ccnc(N)n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)16
Pfam Stratification Cross-Family
Avg pChEMBL6.59
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (16)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 8.4 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 7.2 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 7.1 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 7.0 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.7 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.6 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.5 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.4 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.4 Ki ChEMBL
Q8NE63 HIPK4 Homo sapiens Human PF00069 6.4 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 6.3 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.1 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.1 Ki ChEMBL
P48729 CSNK1A1 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9HBY8 SGK2 Homo sapiens Human PF00069 PF00433 6.0 Ki ChEMBL