Molecule Details
InChIKeySVNVPNHWFJFRLZ-FQEVSTJZSA-N
Compound NameUS10155760, Example 117
Canonical SMILESCOC(=O)Nc1cc(-c2ccc(OC[C@@](C)(N)CC(C)C)c(C(F)F)n2)ccn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL7.02
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
Q2M2I8 AAK1 Homo sapiens Human PF00069 9.0 IC50 ChEMBL;BindingDB
Q9NSY1 BMP2K Homo sapiens Human PF15282 PF00069 7.7 IC50 ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.9 IC50 ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.8 IC50 ChEMBL
O14976 GAK Homo sapiens Human PF00069 PF10409 6.8 IC50 ChEMBL
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.4 IC50 ChEMBL
P53355 DAPK1 Homo sapiens Human PF00023 PF12796 PF13637 PF00531 PF00069 6.2 IC50 ChEMBL
Q8NE63 HIPK4 Homo sapiens Human PF00069 6.2 IC50 ChEMBL