Molecule Details
InChIKeySUULIUKTZNKMMB-UHFFFAOYSA-N
Compound NameN-(1-butyl-5-(N-methylcyclohexanecarboxamido)-1H-benzo[d]imidazol-2-yl)-4-cyanobenzamide
Canonical SMILESCCCCn1c(NC(=O)c2ccc(C#N)cc2)nc2cc(N(C)C(=O)C3CCCCC3)ccc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL6.62
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
Q08881 ITK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 7.8 IC50 ChEMBL;BindingDB
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 7.3 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 7.2 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.7 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q9NWZ3 IRAK4 Homo sapiens Human PF07714 6.3 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.2 Ki ChEMBL
P51957 NEK4 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.1 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.1 Ki ChEMBL