Target not found.
Molecule Details
InChIKeySUGXUUGGLDCZKB-UHFFFAOYSA-N
Compound Name3,4-Dichloroisocoumarin
Canonical SMILESO=c1oc(Cl)c(Cl)c2ccccc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL6.47
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB04459
Drug Name3,4-Dichloroisocoumarin
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan
Categories: Benzopyrans Coumarins Enzyme Inhibitors Heterocyclic Compounds, Fused-Ring Pyrans
Cross-references: BindingDB: 50199883 ChEBI: 109540 CHEMBL24983 ChemSpider: 1550 PDB: DIC PubChem:1609 PubChem:46507031 ZINC: ZINC000000388510
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P08246 ELANE Homo sapiens Human PF00089 7.0 IC50 ChEMBL;BindingDB
P10619 CTSA Homo sapiens Human PF00450 6.2 IC50 ChEMBL;BindingDB
A0A2R3FW87 glpG Haemophilus influenzae Pathogen PF01694 6.2 IC50 BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P00746 CFD Complement factor D binder targets
P08246 ELANE Neutrophil elastase inhibitor targets