Molecule Details
| InChIKey | STJMRWALKKWQGH-UHFFFAOYSA-N |
|---|---|
| Compound Name | Clenbuterol |
| Canonical SMILES | CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.25 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB01407 |
|---|---|
| Drug Name | Clenbuterol |
| CAS Number | 37148-27-9 |
| Groups | approved investigational vet_approved |
| ATC Codes | R03CC13 R03AC14 R03CC63 |
| Description | A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma. |
Categories: Adrenergic Agents Adrenergic Agonists Adrenergic beta-2 Receptor Agonists Adrenergic beta-Agonists Adrenergics for Systemic Use Adrenergics, Inhalants Agents producing tachycardia Agents that produce hypertension Agents to Treat Airway Disease Alcohols Amines Amino Alcohols Anti-Asthmatic Agents Autonomic Agents Bronchodilator Agents Cytochrome P-450 CYP1A1 Substrates Cytochrome P-450 Substrates Drugs for Obstructive Airway Diseases Ethanolamines Long-acting beta-adrenoceptor agonists Neurotransmitter Agents Peripheral Nervous System Agents Respiratory System Agents Selective Beta 2-adrenergic Agonists Sympathomimetics
Cross-references: BindingDB: 27958 ChEBI: 174690 CHEMBL49080 ChemSpider: 2681 Drugs Product Database (DPD): 20239 PharmGKB: PA164745640 PubChem:2783 PubChem:46508373 RxCUI: 2580 Therapeutic Targets Database: DAP000945 Wikipedia: Clenbuterol
Target Activities (2)
DrugBank Target Actions (6)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P04798 | CYP1A1 | Cytochrome P450 1A1 | substrate | enzymes |
| P07550 | ADRB2 | Beta-2 adrenergic receptor | agonist | targets |
| P08588 | ADRB1 | Beta-1 adrenergic receptor | agonist | targets |
| P13945 | ADRB3 | Beta-3 adrenergic receptor | agonist | targets |
| P01375 | TNF | Tumor necrosis factor | other/unknown | targets |
| P01138 | NGF | Beta-nerve growth factor | stimulator | targets |