N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(furan-2-yl)thieno[3,2-d]pyrimidin-4-amine

InChIKey	`SSYMKGVXLKENJR-UHFFFAOYSA-N`
Compound Name	N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(furan-2-yl)thieno[3,2-d]pyrimidin-4-amine
Canonical SMILES	`Fc1cccc(COc2ccc(Nc3ncnc4cc(-c5ccco5)sc34)cc2Cl)c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.0
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	8.0	IC50	ChEMBL;BindingDB
P04626	ERBB2	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	8.0	pIC50	TTD_MultiTarget