Molecule Details
InChIKeySQZJGTOZFRNWCX-UHFFFAOYSA-N
Compound NameElcubragistat
Canonical SMILESO=C(OC(C(F)(F)F)C(F)(F)F)N1CCN(Cc2ccc(C(F)(F)F)cc2N2CCCC2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL7.43
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB16036
Drug NameABX-1431
CAS Number1446817-84-0
Groups investigational
ATC Codes nan
DescriptionABX-1431 is under investigation in clinical trial NCT03625453 (Study of ABX-1431 in Adult Patients With Tourette Syndrome or Chronic Motor Tic Disorder).

Cross-references: BindingDB: 180052 CHEMBL3945728 ChemSpider: 61719539
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q99685 MGLL Homo sapiens Human PF12146 8.3 IC50 ChEMBL;BindingDB
Q9BV23 ABHD6 Homo sapiens Human PF00561 6.6 IC50 ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
Q99685 MGLL Monoglyceride lipase inhibitor targets