Molecule Details
| InChIKey | SQWZFLMPDUSYGV-UHFFFAOYSA-N |
|---|---|
| Compound Name | 5-(6-Quinoxalinylmethylidene)thiazolidine-2,4-dione |
| Canonical SMILES | O=C1NC(=O)C(=Cc2ccc3nccnc3c2)S1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 8 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.15 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (8)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P48736 | PIK3CG | Homo sapiens | Human | PF00454 PF00792 PF00794 PF00613 PF19710 | 8.1 | IC50 | BindingDB |
| Q13627 | DYRK1A | Homo sapiens | Human | PF00069 | 7.5 | IC50 | BindingDB |
| P42336 | PIK3CA | Homo sapiens | Human | PF00454 PF00792 PF02192 PF00794 PF00613 | 7.2 | IC50 | BindingDB |
| P49759 | CLK1 | Homo sapiens | Human | PF00069 | 7.2 | IC50 | BindingDB |
| Q9Y463 | DYRK1B | Homo sapiens | Human | PF00069 | 7.1 | IC50 | BindingDB |
| Q92630 | DYRK2 | Homo sapiens | Human | PF00069 | 7.0 | IC50 | BindingDB |
| P42338 | PIK3CB | Homo sapiens | Human | PF00454 PF00792 PF02192 PF00794 PF00613 | 6.6 | IC50 | BindingDB |
| O00329 | PIK3CD | Homo sapiens | Human | PF00454 PF00792 PF02192 PF00794 PF00613 | 6.5 | IC50 | BindingDB |