Target not found.
Molecule Details
InChIKeySQWZFLMPDUSYGV-POHAHGRESA-N
Compound Name(5Z)-5-(quinoxalin-6-ylmethylidene)-1,3-thiazolidine-2,4-dione
Canonical SMILESO=C1NC(=O)/C(=C/c2ccc3nccnc3c2)S1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)11
Pfam Stratification Cross-Family
Avg pChEMBL7.3
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB04769
Drug Name5-QUINOXALIN-6-YLMETHYLENE-THIAZOLIDINE-2,4-DIONE
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: CHEMBL568150 ChemSpider: 4451248 PDB: QYT PubChem:5289247 PubChem:46508826 ZINC: ZINC000012504504
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
P48736 PIK3CG Homo sapiens Human PF00454 PF00792 PF00794 PF00613 PF19710 8.1 IC50 ChEMBL
P19784 CSNK2A2 Homo sapiens Human PF00069 7.7 IC50 ChEMBL
P67870 CSNK2B Homo sapiens Human PF01214 7.7 IC50 ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 7.7 IC50 ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 7.5 IC50 ChEMBL
P42336 PIK3CA Homo sapiens Human PF00454 PF00792 PF02192 PF00794 PF00613 7.2 IC50 ChEMBL
P49759 CLK1 Homo sapiens Human PF00069 7.2 IC50 ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 7.1 IC50 ChEMBL
Q92630 DYRK2 Homo sapiens Human PF00069 7.0 IC50 ChEMBL
P42338 PIK3CB Homo sapiens Human PF00454 PF00792 PF02192 PF00794 PF00613 6.6 IC50 ChEMBL
O00329 PIK3CD Homo sapiens Human PF00454 PF00792 PF02192 PF00794 PF00613 6.5 IC50 ChEMBL
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P27338 MAOB Amine oxidase [flavin-containing] B inhibitor targets
P48736 PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform inhibitor targets